See several of the best cities in America
North America is a sprawling continent, teeming with diverse landscapes, cultures, and iconic cities waiting to be explored. Why confine yourself to just one destination when you can embark on a journey through some of the most thrilling cities across the USA? Our exceptional multi-centre holidays offer the perfect solution to experiencing the best of both worlds.
Imagine seamlessly transitioning from the bustling streets of New York City to the vibrant nightlife of Las Vegas, or to the architectural marvels of Chicago, the historical landmarks of Washington D.C., or the laid-back vibes of Los Angeles. Our multi-centre holidays provide an unparalleled opportunity to explore multiple facets of the United States.
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Special Offers
Take advantage of the following offers on an America multi-centre holiday

Save up to £500 per booking
Book by 30th June and take advantage of our exclusive savings
• Save £500 on bookings over £10,000
• Save £350 on bookings between £7,500 - £9,999
• Save £300 on bookings between £5,000 - £7,499
• Save £250 on bookings between £2,500 - £4,999
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Recommended Holidays
Explore a collection of our handpicked multi-centre holidays below

Great US Eastern Cities by Rail
Perfect for non-drivers, this rail tour includes historic Boston, the pulsating beat of New York City and the powerful US capital city of Washington DC.
9 Nights From
£1,315
ppOverview
Perfect for non-drivers, this rail tour includes historic Boston, the pulsating beat of New York City and the powerful US capital city of Washington DC.
What’s included?
- International flights departing from the UK in economy class.
- 9 nights hotel accommodation
- Amtrak train from Boston to New York City in Coach Class
- Amtrak train from New York City to Washington DC in Coach Class

The Golden Triangle - San Francisco, Vegas & LA
Sample the “Best of the West” with this holiday linking the three iconic west coast cities in one trip.
10 Nights From
£1,441
ppOverview
Sample the “Best of the West” with this holiday linking the three iconic west coast cities in one trip.
What’s included?
- International flights from the UK based on economy class
- Domestic flights between San Francisco and Las Vegas
- Domestic flights between Las Vegas and Los Angeles
- Accommodation for 10 nights

Las Vegas & A Taste of the National Parks
This holiday is perfect for those who want to experience some of America’s most mesmerizing national parks travelling in a small group.
7 Nights From
£1,687
ppOverview
This holiday is perfect for those who want to experience some of America’s most mesmerizing national parks travelling in a small group.
What’s included?
- International flights from the UK based on economy class
- Accommodation for 5 nights
- 2 nights small group tour with Max Tours escorted by an experienced guide
- 3 breakfasts, 2 lunches, 1 dinner and unlimited water, drinks and snacks

Best of the West - San Francisco, LA, Las Vegas & the Grand Canyon
Perfect for travellers short on time, this bucket list getaway takes you to San Francisco, Los Angeles, Las Vegas, and the Grand Canyon.
10 Nights From
£1,817
ppOverview
Perfect for travellers short on time, this bucket list getaway takes you to San Francisco, Los Angeles, Las Vegas, and the Grand Canyon.
What’s included?
- International flights from the UK based on economy class
- Domestic flights between San Francisco and Las Vegas
- Domestic flights between Las Vegas and Los Angeles
- Accommodation for 8 nights
- 2 nights small group tour with MaxTour escorted by an experienced guide
- 3 breakfasts, 2 lunches, 1 dinner and unlimited water, drinks and snacks

Eastern Delights - New York, Toronto & Niagara Falls
Visiting three of the most iconic cities and natural wonders in North America, this tour includes undoubtedly one of the most exciting cities in the world - New York - before taking you on a short flight to Toronto which sits on beautiful Lake Ontario. With a grand finale of the splendour of Niagara Falls and included sightseeing, this is tour has it all.
8 Nights From
£2,079
ppOverview
Visiting three of the most iconic cities and natural wonders in North America, this tour includes undoubtedly one of the most exciting cities in the world - New York - before taking you on a short flight to Toronto which sits on beautiful Lake Ontario. With a grand finale of the splendour of Niagara Falls and included sightseeing, this is tour has it all.
What’s included?
- International flights from the UK based on economy class
- Accommodation for 8 nights
- New York CityPass
- Admission to the CN Tower in Toronto
- Voyage to the Falls Boat Tour in Niagara Falls
- Scheduled transfers from your Toronto hotel to Niagara Falls and from Niagara Falls to Toronto Airport

New York, Beautiful Cape Cod & Martha's Vineyard
This delightful rail and fly-drive tour encompasses the electric and one-of-a-kind city of New York with the historic city of Boston, before driving south to popular Cape Cod and the unspoilt and exclusive island of Martha’s Vineyard.
10 Nights From
£2,311
ppOverview
This delightful rail and fly-drive tour encompasses the electric and one-of-a-kind city of New York with the historic city of Boston, before driving south to popular Cape Cod and the unspoilt and exclusive island of Martha’s Vineyard.
What’s included?
- International flights from the UK based on economy class
- Accommodation for 10 nights
- Amtrak from New York to Boston in Coach class
- Return ferry crossing from Woods Hole to Martha’s Vineyard
- 6 days compact car hire with fully inclusive insurance, unlimited mileage and taxes

California Cities & Hawaiian Island Hopping
From the excitement of San Francisco and Los Angeles to the majestic peak of Mauna Kea on the Big Island of Hawaii, this holiday has it all.
16 Nights From
£2,605
ppOverview
From the excitement of San Francisco and Los Angeles to the majestic peak of Mauna Kea on the Big Island of Hawaii, this holiday has it all.
What’s included?
- International flights from the UK based on economy class
- Domestic flights in the USA in economy class
- Accommodation for 16 nights

Hawaii's Paradise - An Island Hopping Adventure
Paradise awaits on this island-hopping holiday that visits the stunning and unique islands of Hawaii. Witness spectacular sunsets, relax on golden sand beaches and get up close to dramatic scenery that will take your breath away.
15 Nights From
£3,414
ppOverview
Paradise awaits on this island-hopping holiday that visits the stunning and unique islands of Hawaii. Witness spectacular sunsets, relax on golden sand beaches and get up close to dramatic scenery that will take your breath away.
What’s included?
- International flights departing from London in economy class
- Transpacific and inter-island flights in economy class
- Accommodation for 15 nights
Get in touch
Our team of experts are on hand to craft your perfect multi-centre holiday.
Request a quoteExplore Multi-Centre Holidays
Overview
Each city offers its own unique blend of attractions, from world-class museums and iconic landmarks to thriving culinary scenes and outdoor adventures. With our meticulously planned itineraries, all logistics including transfers between cities and accommodations in handpicked 3-star or 4-star hotels are taken care of. This means you can focus entirely on immersing yourself in each destination without the stress of planning or navigating unfamiliar surroundings.
Our carefully curated packages are designed to maximise your time and enhance your travel experience. Whether you're a city enthusiast, nature lover, or cultural explorer, our multi-centre holidays ensure you can savour the diversity and excitement of America with ease. Discover our range of multi-centre holidays and create your own unforgettable adventures across the United States.
America Multi-Centre Holidays FAQs
Multi-centre America holidays allow you to combine multiple destinations into one seamless journey. From the lively streets of New York to the serene vistas of the Grand Canyon, experience the best the US has to offer.
If you are planning a fly drive holiday in America and are wondering how difficult it is to drive in the country, then you don’t need to worry. The roads in America are generally very wide and of a high quality and the rules of the road are very similar to that of the UK. The one major difference is that in America, you will be driving on the right side of the road.
You don’t need to organise a Canada fly drive itinerary, you can speak to our Canada travel experts and tell them where you would like to go. We will do the rest of the groundwork and tailor-make the perfect trip for you.
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Expert Advice
A multicentre holiday is the ultimate way to pack in multiple destinations into one epic trip. Instead of sticking to just one spot, explore different cities, landscapes, and cultures all in one go. This way you can hit multiple travel bucket list items at once, plus it often saves you money compared to booking separate trips.
Book with peace of mind
You can be rest assured that when you book with American Affair you can book with complete confidence due to the safeguarding measures we have in place:
- ABTA / ATOL Protection: We are both ATOL protected and members of ABTA.
- Money in trust: Your money is held in a secure trust fund and is only released to us when you return from your holiday.
- Out of hours support: Our out of hours in-resort emergency line means we are always on hand if you need assistance.
- Credit score: We are assessed by Creditsafe and have obtained an A rating which is classed as 'very low risk'.

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